© Fraunhofer IPA
…was developed at the Fraunhofer Institute for Manufacturing Engineering and Automation in Mannheim. ⇒
It facilitates a standardized sample preparation with subsequent filtration in a closed, sterile system, based on standard labware.
A benchtop-device with four grinding slots allows customizable process control for the mechanical dissociation, yielding high quality single cell suspensions from fresh or frozen or even FFPE tissue samples, which can be used for a multitude of applications.
By employing an ideal combination of shearing and cutting forces, highly viable cells can be obtained for cytometry, further cytological and molecular analysis or cultivation.
© Fraunhofer IPA
…was developed at the Fraunhofer Institute for Manufacturing Engineering and Automation in Mannheim. ⇒
It facilitates a standardized sample preparation with subsequent filtration in a closed, sterile system, based on standard labware.
A benchtop-device with four grinding slots allows customizable process control for the mechanical dissociation, yielding high quality single cell suspensions from fresh or frozen or even FFPE tissue samples, which can be used for a multitude of applications.
By employing an ideal combination of shearing and cutting forces, highly viable cells can be obtained for cytometry, further cytological and molecular analysis or cultivation.
© Fraunhofer IPA
The TissueGrinder is able to dissociate a great variety of tissue types in different conditions – healthy, tumorous, fresh, frozen or even FFPE*.
The mechanical process of the TissueGrinder matches or even outperforms the best enzymatic protocols in terms of cell yield and viability
The TissueGrinder is able to dissociate a great variety of tissue types in different conditions – healthy, tumorous, fresh, frozen or even FFPE*.
Generating high quality single cells from tissue samples is a real bottleneck for many applications, such as Flow Cytometry, Single Cell Sequencing, Isolation of Primary Cells, Cancer Cell Line Development to name a few.
Conventional tissue dissociation is is either time-consuming, non-standardized, not scalable or accepting all drawbacks of enzymatic digestion. Or all of them together.
With the TissueGrinder, this bottleneck can be overcome and the door to a new level in single cell analysis can be opened wide.
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